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Monday 25 November 2013

History, applications of hormones, cosmetics & personal care, pharmaceuticals & medicinal products

Types of hormones, cosmetics & personal care products,  pharmaceuticals chemicals


Biochemicals, chemical messengers, mood swingers, plant growth regulators what ever may be the names for hormones plays vital role in humans, animals and even in plants. Hormones produced in one part of body/place and travel through bloodstream to different parts of the body.

Hormones basically involved in



  • Growth – in humans, animals and plants
  • Digestion process – in humans, animals
  • Metabolism – in humans, animals
  • Mood changes – in humans
  • Sexual development – in humans, animals
  • Reproduction process – in humans, animals, plants

By this functions hormones are divided into following two groups


Hormones also classified based on their origin. These are

  • Peptide hormones
  • Lipids derived hormones
  • Phospholipids derived hormones
  • Any sort of imbalances in hormone levels can causes
  • Anxiety
  • Sleep Disorders
  • Depression
  • Poor concentration
  • Nervousness
  • Skin Problems etc
  • Plant hormones

Plant hormones also has important functions

  • Auxins – helps in vegetative propagation
  • Cytokinins – for cell division, root proliferation
  • Gibberellins – for flowering, seed dormancy
  • Abscisic Acid – for abscission of flowers, leaves, fruits
  • Ethylene – for fruit ripening
  • Polyamines – to promote plant regeneration

Human hormones

In various human development stages hormonal secretion levels will change. At the age of 10 to 11 years in humans, hormones related to puberty leads to change in mental and physical growth.

Still in teenagers hormones causes

  • Self-consciousness
  • Quick mood changes
  • Quick decision changes
  • Attraction towards opposite genders

At the age of teenage people will fall in love, reason behind this is all because of high levels of hormones. There are certain stages of love

  • Lust
  • Attraction towards opposite gender
  • Commitment

All these emotions are because of love chemicals. These love chemicals include



Adrenaline – causes excitement, attraction,anxiety
Estrogen – sex drive factor in both male and females
Testosterone - sex drive factor in both male and females
Dopamine – it’s a pleasure chemical
Norepinephrine – raises excitement in heart
Serotonin – released attraction stage of love
Oxytocin – for long term relationships between couples
Vasopressin – vital role in long-term commitment
Endorphins – causes feelings like attachment, comfort, anxiety, relieve stress, relieve pain

Cosmetics and personal care products

Human’s skin is the largest organ in their body and when you apply cosmetics, personal care products, perfumes, fragrances it will absorb soon and show immediate results.

So most of the teenage people both genders shows interest in body cleansing, beautifying, promoting attractiveness, altering the appearance. These type of products termed as cosmetics and personal care products.

Cosmetic and personal care products are applied to appear more attraction and look different from others.

Cosmetic products used in the form of powders, solutions, gels, suspensions, pastes, lotions. These products can be used starting from head to toe of human body.

Chemicals involved in the preparation of cosmetics and personal care include


Cosmetic manufacturers before releasing their products into market they will be testing for safety and efficacy on animals like mice, guinea pigs, rats, and rabbits. Some cosmetic manufacturers remove controversial and hazardous chemicals from their cosmetic products.

Along with the cosmetic products people widely use perfumes, fragrances to their body, cloths.

All civilizations, from ancient to contemporary world, have used fragrances for a wide spread of functions. Before the appearance of organic synthesis, fragrances were restricted to those found in the form of oils, balsams, exudates, and resins. With development of organic synthesis during the 19th Century, fragrance chemistry advanced into industrial synthesis and distribution.

Usage of fragrances was started by Egyptians, Greeks, Rome people and it continues in 20th centaury. The ancient people prepared cosmetics and personal care products from herbs, plant sources.

A fragrance was also used for tombs to preserve human body, antidotes for toxins, health improver agents.

Some perfumes according to their chemical composition and origin from where they derived or extracted stays on body and even they will exerts perfumery action with immediate or slow response.

Fragrance chemistry is an ever dynamic field that relies on the trends of the age. Recent trends in fragrance chemistry include floral scents, fruity scents, spicy scents, rose flower scents. Fragrance chemistry is an industrially important science that needs the constant discovery of new and distinctive odorants.

Fragrances are classified into following type based on origin


Most of the synthetic fragrances are made of

  • Terpenoids – GeraniolLinalool, Citronellol, Citronellal, Citral
  • Hemiterpenoids – Prenyl acetate, Benzoate
  • Cyclic Monoterpenes - l-menthol, l-carvone, α-terpineol
  • Menthol
  • Bicyclic Monoterpenoids – Camphene
  • Sesquiterpenoids – Geranylacetone, Bisabolol
  • Diterpenoids
  • Ambergris
  • Benzoin
  • Calone
  • Castoreum
  • Hedione
  • Indole

At teenage level due to peek hormonal levels some people will addicted to drugs. This is termed as drug addiction or substance addiction.

Neurochemicals or neurotransmitters like dopamine and serotonin are the real culprit behind drug addiction. Dopamine motivates us to do what’s necessary to fulfill our desires, and once a desire has been met, the nucleus accumbens triggers the release of serotonin. Serotonin, which helps us feel satiated and contributes to feelings of happiness and well-being, then inhibits the compelling motivation of dopamine.

Once people habituated to taking drugs, there is a possibility of decline of their health. To treat their health pharmaceuticals or drugs or medicines or chemotherapeutic agents required.

So pharmaceuticals or drugs can be defined as ‘chemicals substances that are used in medical diagnosis, curing, treatment, prevention in humans, animals, and plants’.

Pharmaceutical manufacturers produce drugs/medicines and released into the market. Before releasing the drugs into market pharmaceutical manufacturers will conduct following tests/studies on animals, healthy volunteers. Basically in theses studies scientists check for the safety, efficacy, pharmacodynamics and pharmacokinetics of drugs.

  • Pre-clinical studies
  • Phase I
  • Phase II
  • Phase III
  • Post market Surveillance

Drugs used for chemotherapy or pharmacotherapy are divided based on the purpose of use

  • Veterinary drugs
  • Musculoskeletal drugs
  • Hormonal drugs
  • Antidotes
  • Antiparasitic drugs
  • Antibiotics
  • Antineoplastic drugs
  • Dermatological drugs
  • Gastrointestinal drugs
  • Cardiovascular drugs
  • Proton pump inhibitor drugs
  • Pharmaceutical raw materials
  • Pharmaceutical intermediates


Veterinary medicine given to both domestic animals, wild animals for the purpose of prevention and treatment of diseases. Veterinary medicine given to animals through via feed, water, nervous system.

Musculoskeletal drugs

Musculoskeletal drugs diagnose acute, sub-acute and chronic non-surgical musculoskeletal complaints like pain in the muscles, tendons, ligaments and joints.


Hormone drugs are hormone replacements for patients with thyroid problems and other hormonal imbalance problems. Hormonal medicine also used for regulation of ovulation and menstruation.


Antidote are pharmaceuticals neutralizes counteracts with harmful effects of poison. Antihistamines used for seasonal allergic itching, hay fever, reduces nausea, vomiting, anaphylaxis.

Antiparasitic drugs

Antiparasitic drugs are pharmaceuticals diseases caused by nematodes, cestodes, trematodes, protozoa, and amoeba. Antiparasitic drugs are highly effective, safe, cost effective drugs.


Antibiotics works selectively by killing particular type of bacteria without harming living cells. Antibiotics interfere with the formation of the bacterium’s cell wall or its cell contents there by it kill or prevent the growth of bacteria.


Anticancer drugs also termed as antineoplastic agents. Anticancer drugs effective for hormone-sensitive tumors, malignancies, cancerous cells growth. Anticancer drugs acts at specific points of the anaphase or metaphase of cell cycle.

Dermatological drugs

Dermatological drugs exert chemical physical action on the skin in order to assist in treatment of skin diseases. Dermatological drugs composed with other medicines like local anesthetics, cleansing agents, anti-inflammatory agents, anti-infective agents, emollients, and astringents, agents to treat acne, anti-virals, and anti-fungal.


Gastrointestinal drugs are pharmaceuticals neutralize the acid secretions of stomach, regulates gastrointestinal motility, improve digestion and stimulate the production of bile by the liver. Naproxen, ranitidine, clebopride, betazole, impromidine are widely used gastrointestinal agents.


Cardiovascular drugs are pharmaceuticals cures cardiovascular diseases heart attack, stroke, hypertension, congestive heart failure and vascular death. Digoxin, bisoprolol, lidocaine, midodrine are widely used cardiovascular drugs.


Proton pump inhibitors are pharmaceuticals works against acid refluxes in stomach walls, peptic ulcers, and stomach ulcers. Nexium, Prilosec, Protonix, Prevacid, AcipHex, Kapidex is the commonly used proton pump inhibitors drug brands.


Pharmaceutical raw materials are two type’s active ingredients and inactive ingredients. Pharmaceutical raw materials are needed to make medicines and drugs. Inactive ingredients are ineffective pharma raw materials used to create pills.


Pharmaceutical intermediates are fine chemical products and important principle ingredients in manufacturing of synthetic medicines.

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